6-[(tert-Butoxycarbonyl)amino]spiro[3.3]heptane-2-carboxylic acid ethyl ester - B6147
6-[(tert-Butoxycarbonyl)amino]spiro[3.3]-heptane-2-carboxylic acid ethyl ester
CAS: 1272412-66-4
Molecular Formula: C15H25NO4
6-[(tert-Butoxycarbonyl)amino]spiro[3.3]heptane-2-carboxylic acid ethyl ester - B6147 - Names and Identifiers
6-[(tert-Butoxycarbonyl)amino]spiro[3.3]heptane-2-carboxylic acid ethyl ester - B6147 - Physico-chemical Properties
| Molecular Formula | C15H25NO4 |
| Molar Mass | 283.36 |
| Storage Condition | 2-8℃ |
| Sensitive | Irritant |
| MDL | MFCD17016158 |
6-[(tert-Butoxycarbonyl)amino]spiro[3.3]heptane-2-carboxylic acid ethyl ester - B6147 - Introduction
6-[(tert-Butoxycarbonyl)amino]spiro[3.3]-heptane-2-carboxylic acid ethyl ester is a compound whose chemical formula is C15H27NO4.
Nature:
-Appearance: Colorless liquid.
-Melting point:-5°C.
-Boiling point: 218-220°C.
-Density: 1.062g/cm3.
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide.
Use:
- 6-[(tert-Butoxycarbonyl)amino]spiro[3.3]-heptane-2-carboxylic acid ethyl ester is commonly used in the field of drug synthesis as an intermediate or raw material.
-It can be used to synthesize biologically active compounds for drug research and development.
Preparation Method:
- 6-[(tert-Butoxycarbonyl)amino]spiro[3.3]-the preparation method of heptane-2-carboxylic acid ethyl ester is complicated and often requires multi-step reactions. A common synthesis method includes the following steps:
1. Tert-butyl bromoformate and caprolactam react to generate 6-caprolactamyl pentane -1-acid ethyl ester.
2. reacting the compound obtained in the previous step with dimethyl sodium p-toluenesulfonate to generate tert-butyrylamino ethyl o-benzenesulfonate.
3. reduce the compound obtained in the previous step with sodium hydride and graphite catalyst to obtain 6-[(tert-Butoxycarbonyl)amino]spiro[3.3]-heptane-2-carboxylic acid ester.
Safety Information:
- 6-[(tert-Butoxycarbonyl)amino]spiro[3.3]-heptane-2-carboxylic acid ethyl ester may be irritating to the eyes, skin and respiratory tract and should be paid attention to when exposed.
-When using or handling the compound, follow relevant safety practices, such as wearing protective glasses, gloves and respiratory protection equipment.
-If contact or inhalation occurs, wash the affected area immediately and seek medical help when needed.
-When handling or storing this compound, avoid contact with oxidants, high temperatures and open flames.
Nature:
-Appearance: Colorless liquid.
-Melting point:-5°C.
-Boiling point: 218-220°C.
-Density: 1.062g/cm3.
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide.
Use:
- 6-[(tert-Butoxycarbonyl)amino]spiro[3.3]-heptane-2-carboxylic acid ethyl ester is commonly used in the field of drug synthesis as an intermediate or raw material.
-It can be used to synthesize biologically active compounds for drug research and development.
Preparation Method:
- 6-[(tert-Butoxycarbonyl)amino]spiro[3.3]-the preparation method of heptane-2-carboxylic acid ethyl ester is complicated and often requires multi-step reactions. A common synthesis method includes the following steps:
1. Tert-butyl bromoformate and caprolactam react to generate 6-caprolactamyl pentane -1-acid ethyl ester.
2. reacting the compound obtained in the previous step with dimethyl sodium p-toluenesulfonate to generate tert-butyrylamino ethyl o-benzenesulfonate.
3. reduce the compound obtained in the previous step with sodium hydride and graphite catalyst to obtain 6-[(tert-Butoxycarbonyl)amino]spiro[3.3]-heptane-2-carboxylic acid ester.
Safety Information:
- 6-[(tert-Butoxycarbonyl)amino]spiro[3.3]-heptane-2-carboxylic acid ethyl ester may be irritating to the eyes, skin and respiratory tract and should be paid attention to when exposed.
-When using or handling the compound, follow relevant safety practices, such as wearing protective glasses, gloves and respiratory protection equipment.
-If contact or inhalation occurs, wash the affected area immediately and seek medical help when needed.
-When handling or storing this compound, avoid contact with oxidants, high temperatures and open flames.
Last Update：2024-04-09 19:06:02
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